' 
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: About 1/4 cup (31 g)
Amount Per Serving
%DV
Calories
180
Total Fat
13 g
17%
Saturated Fat
3 g
15%
Trans Fat
0 g
Cholesterol
0 mg
0%
Sodium
0 mg
0%
Total Carbohydrate
4 g
1%
Dietary Fiber
2 g
7%
Total Sugars
0 g
Includes 0g Added Sugars
0%
Protein
11g
Vit. D
0 mcg
0%
Calcium
8 mg
0%
Iron
4 mg
20%
Potassium
243 mg
6%
Top Medical Research Studies
9
Protein treatment shows promise
Prolyl hydroxylase domain inhibitors prevent kidney crystal formation by suppressing inflammation.
Study evaluates kidney stone treatment
We explored how a specific type of treatment called prolyl hydroxylase domain inhibitors, particularly roxadustat, impacts the formation of kidney stones. The study used both lab-based experiments and live mouse models to understand how this treatment might help reduce the damaging inflammation associated with the formation of calcium oxalate crystals in the kidneys.
In the lab, we subjected murine renal tubular cells to roxadustat while exposing them to calcium oxalate crystals. Our findings showed that roxadustat effectively limited the adhesion of these harmful crystals to the cells and decreased levels of various proinflammatory proteins that can worsen kidney damage. Additionally, we looked at the interaction between these cells and immune macrophages, noting that roxadustat reduced the inflammatory response in this group as well.
In our in vivo trials with mice, we injected them with roxadustat and found that those treated with the drug had significantly fewer calcium oxalate deposits in their kidneys compared to those receiving saline. Overall, roxadustat appeared to reduce both kidney inflammation and the formation of stones, suggesting it could be a promising treatment option for preventing kidney stones in humans as well.
In the lab, we subjected murine renal tubular cells to roxadustat while exposing them to calcium oxalate crystals. Our findings showed that roxadustat effectively limited the adhesion of these harmful crystals to the cells and decreased levels of various proinflammatory proteins that can worsen kidney damage. Additionally, we looked at the interaction between these cells and immune macrophages, noting that roxadustat reduced the inflammatory response in this group as well.
In our in vivo trials with mice, we injected them with roxadustat and found that those treated with the drug had significantly fewer calcium oxalate deposits in their kidneys compared to those receiving saline. Overall, roxadustat appeared to reduce both kidney inflammation and the formation of stones, suggesting it could be a promising treatment option for preventing kidney stones in humans as well.
Read More
9
Protein role in kidney stones
Inhibiting brushite crystal growth: molecular docking exploration of phytoconstituents and their interaction with human serum albumin.
Moderate focus on protein interaction
We examined how protein, specifically human serum albumin (HSA), interacts with certain phytoconstituents to potentially inhibit the formation of kidney stones, particularly brushite crystals. The research involved molecular docking techniques, where we analyzed 35 different phytochemicals to see how they bind with HSA.
Our findings highlighted Baicalein-7-O-glucoside as the star compound, demonstrating a strong binding affinity that suggests it could effectively modulate HSA's role in promoting crystal growth. We conducted extensive follow-up analyses, including Induced Fit Docking and Molecular Dynamics simulations over a span of 50 nanoseconds, to ensure the stability of this complex.
Additionally, our assessments indicated that the top compounds showed promising drug-like properties and good biological profiles. Overall, we discovered that specific polyphenolic compounds might play a role in reducing than enhancing the risk of kidney stones by influencing how HSA interacts during the crystallization process.
Our findings highlighted Baicalein-7-O-glucoside as the star compound, demonstrating a strong binding affinity that suggests it could effectively modulate HSA's role in promoting crystal growth. We conducted extensive follow-up analyses, including Induced Fit Docking and Molecular Dynamics simulations over a span of 50 nanoseconds, to ensure the stability of this complex.
Additionally, our assessments indicated that the top compounds showed promising drug-like properties and good biological profiles. Overall, we discovered that specific polyphenolic compounds might play a role in reducing than enhancing the risk of kidney stones by influencing how HSA interacts during the crystallization process.
Read More
9
Peptide nanoparticles aid kidney health
Annexin-derived self-assembling peptide nanostructures for alleviation of calcium oxalate -induced renal injury.
Protein treatment relevant but complex
We explored the potential of a specially designed peptide from Annexin A1, which is known for its ability to bind calcium, in addressing kidney stone formation. Kidney stones often start as polycrystalline aggregates, and calcium oxalate monohydrate is the most common type we see.
In our research, we focused on how this peptide could help alleviate the harmful effects of calcium oxalate crystals in the kidneys. By developing a salt-dependent method, we created self-assembling spherical nanoparticles from a specific peptide sequence. This sequence had a net negative charge and was designed to maintain its interaction with the calcium oxalate interface.
The results were promising. We found that these peptide nanoparticles improved cell viability and lowered oxidative stress in kidney cells exposed to calcium oxalate crystals. Additionally, they seemed to protect the urinary system by enhancing urinary biochemistry while reducing calcifications, without causing any toxicity.
However, while we noted these benefits, it’s essential to remain cautious about interpreting the results, as other factors might influence the outcomes. Overall, this study suggests that using calcium-binding peptides may provide a novel approach to tackling kidney stones effectively.
In our research, we focused on how this peptide could help alleviate the harmful effects of calcium oxalate crystals in the kidneys. By developing a salt-dependent method, we created self-assembling spherical nanoparticles from a specific peptide sequence. This sequence had a net negative charge and was designed to maintain its interaction with the calcium oxalate interface.
The results were promising. We found that these peptide nanoparticles improved cell viability and lowered oxidative stress in kidney cells exposed to calcium oxalate crystals. Additionally, they seemed to protect the urinary system by enhancing urinary biochemistry while reducing calcifications, without causing any toxicity.
However, while we noted these benefits, it’s essential to remain cautious about interpreting the results, as other factors might influence the outcomes. Overall, this study suggests that using calcium-binding peptides may provide a novel approach to tackling kidney stones effectively.
Read More
Most Useful Reviews
9.5
Natural diuretic benefit
Pumpkin seeds are a potent natural diuretic. They assist in eliminating kidney stones and can help prevent urolithiasis. Traditional remedies often recommend a decoction of crushed pumpkin and flax seeds for urinary issues, cystitis, cholecystitis, and various bladder concerns.
Read More
8.8
Help with kidney stones
Yum! I eat these to aid with kidney stones. They are fresh, plump, and taste delightful! I also utilise them in cooking.
Read More
Most Recommended Products for Kidney Stones
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 3 Researches
9
9
Protein treatment shows promise
Prolyl hydroxylase domain inhibitors prevent kidney crystal formation by suppressing inflammation.
Study evaluates kidney stone treatment
We explored how a specific type of treatment called prolyl hydroxylase domain inhibitors, particularly roxadustat, impacts the formation of kidney stones. The study used both lab-based experiments and live mouse models to understand how this treatment might help reduce the damaging inflammation associated with the formation of calcium oxalate crystals in the kidneys.
In the lab, we subjected murine renal tubular cells to roxadustat while exposing them to calcium oxalate crystals. Our findings showed that roxadustat effectively limited the adhesion of these harmful crystals to the cells and decreased levels of various proinflammatory proteins that can worsen kidney damage. Additionally, we looked at the interaction between these cells and immune macrophages, noting that roxadustat reduced the inflammatory response in this group as well.
In our in vivo trials with mice, we injected them with roxadustat and found that those treated with the drug had significantly fewer calcium oxalate deposits in their kidneys compared to those receiving saline. Overall, roxadustat appeared to reduce both kidney inflammation and the formation of stones, suggesting it could be a promising treatment option for preventing kidney stones in humans as well.
In the lab, we subjected murine renal tubular cells to roxadustat while exposing them to calcium oxalate crystals. Our findings showed that roxadustat effectively limited the adhesion of these harmful crystals to the cells and decreased levels of various proinflammatory proteins that can worsen kidney damage. Additionally, we looked at the interaction between these cells and immune macrophages, noting that roxadustat reduced the inflammatory response in this group as well.
In our in vivo trials with mice, we injected them with roxadustat and found that those treated with the drug had significantly fewer calcium oxalate deposits in their kidneys compared to those receiving saline. Overall, roxadustat appeared to reduce both kidney inflammation and the formation of stones, suggesting it could be a promising treatment option for preventing kidney stones in humans as well.
Read More
9
Protein role in kidney stones
Inhibiting brushite crystal growth: molecular docking exploration of phytoconstituents and their interaction with human serum albumin.
Moderate focus on protein interaction
We examined how protein, specifically human serum albumin (HSA), interacts with certain phytoconstituents to potentially inhibit the formation of kidney stones, particularly brushite crystals. The research involved molecular docking techniques, where we analyzed 35 different phytochemicals to see how they bind with HSA.
Our findings highlighted Baicalein-7-O-glucoside as the star compound, demonstrating a strong binding affinity that suggests it could effectively modulate HSA's role in promoting crystal growth. We conducted extensive follow-up analyses, including Induced Fit Docking and Molecular Dynamics simulations over a span of 50 nanoseconds, to ensure the stability of this complex.
Additionally, our assessments indicated that the top compounds showed promising drug-like properties and good biological profiles. Overall, we discovered that specific polyphenolic compounds might play a role in reducing than enhancing the risk of kidney stones by influencing how HSA interacts during the crystallization process.
Our findings highlighted Baicalein-7-O-glucoside as the star compound, demonstrating a strong binding affinity that suggests it could effectively modulate HSA's role in promoting crystal growth. We conducted extensive follow-up analyses, including Induced Fit Docking and Molecular Dynamics simulations over a span of 50 nanoseconds, to ensure the stability of this complex.
Additionally, our assessments indicated that the top compounds showed promising drug-like properties and good biological profiles. Overall, we discovered that specific polyphenolic compounds might play a role in reducing than enhancing the risk of kidney stones by influencing how HSA interacts during the crystallization process.
Read More
9
Peptide nanoparticles aid kidney health
Annexin-derived self-assembling peptide nanostructures for alleviation of calcium oxalate -induced renal injury.
Protein treatment relevant but complex
We explored the potential of a specially designed peptide from Annexin A1, which is known for its ability to bind calcium, in addressing kidney stone formation. Kidney stones often start as polycrystalline aggregates, and calcium oxalate monohydrate is the most common type we see.
In our research, we focused on how this peptide could help alleviate the harmful effects of calcium oxalate crystals in the kidneys. By developing a salt-dependent method, we created self-assembling spherical nanoparticles from a specific peptide sequence. This sequence had a net negative charge and was designed to maintain its interaction with the calcium oxalate interface.
The results were promising. We found that these peptide nanoparticles improved cell viability and lowered oxidative stress in kidney cells exposed to calcium oxalate crystals. Additionally, they seemed to protect the urinary system by enhancing urinary biochemistry while reducing calcifications, without causing any toxicity.
However, while we noted these benefits, it’s essential to remain cautious about interpreting the results, as other factors might influence the outcomes. Overall, this study suggests that using calcium-binding peptides may provide a novel approach to tackling kidney stones effectively.
In our research, we focused on how this peptide could help alleviate the harmful effects of calcium oxalate crystals in the kidneys. By developing a salt-dependent method, we created self-assembling spherical nanoparticles from a specific peptide sequence. This sequence had a net negative charge and was designed to maintain its interaction with the calcium oxalate interface.
The results were promising. We found that these peptide nanoparticles improved cell viability and lowered oxidative stress in kidney cells exposed to calcium oxalate crystals. Additionally, they seemed to protect the urinary system by enhancing urinary biochemistry while reducing calcifications, without causing any toxicity.
However, while we noted these benefits, it’s essential to remain cautious about interpreting the results, as other factors might influence the outcomes. Overall, this study suggests that using calcium-binding peptides may provide a novel approach to tackling kidney stones effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
9.5
Natural diuretic benefit
Pumpkin seeds are a potent natural diuretic. They assist in eliminating kidney stones and can help prevent urolithiasis. Traditional remedies often recommend a decoction of crushed pumpkin and flax seeds for urinary issues, cystitis, cholecystitis, and various bladder concerns.
8.8
Help with kidney stones
Yum! I eat these to aid with kidney stones. They are fresh, plump, and taste delightful! I also utilise them in cooking.
